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  6. 3M™ Emphaze™ AEX Series Hybrid Purifier, BV1R, EMP201AEX020R, 4/Case

3M™ Emphaze™ AEX Series Hybrid Purifier, BV1R, EMP201AEX020R, 4/Case

3M ID 7100174193
  • Reduces turbidity, HCP, DNA and bioburden.
  • Excellent throughput and mAb recovery.
  • Enhanced capture column performance and protection.
  • Substantial turbidity, DNA, HCP and bioburden reduction.
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Specifications
Applications
Adsorptive Depth Filtration, Bioburden Reduction, Cell Culture Clarification, Chromatography and Column Protection, DNA Removal, Plasma Fractionation
Brand
Emphaze™
Filter Type
Filter Capsule
Flow Rate (metric)
1 Millilitre per Minute
Industries
Life Sciences
Maximum Operating Temperature (Celsius)
40 Degree Celsius
Product Series
AEX
Series
Emphaze™ AEX
Storage Temperature
68
Units per Case
4
Product Details
  • Reduces turbidity, HCP, DNA and bioburden.
  • Excellent throughput and mAb recovery.
  • Enhanced capture column performance and protection.
  • Substantial turbidity, DNA, HCP and bioburden reduction.
  • Reduced surface area requirement of the downstream sterilizing grade membrane.
  • May offer differentiated protection of the protein A column for enhanced contaminant clearance performance.
  • All product components comply with United States Pharmacopeia (USP) Class VI 70°C Biological Reactivity Tests, in vivo.

3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier.

The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer.

The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule.

Capsules
There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules:

  • The Laboratory capsule (BV8) has an 8ml bed volume.
  • The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively).
  • The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use.

A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.

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